منابع مشابه
MicroRNAs Regulate Brain Morphogenesis in Zebrafish Antonio
14. J. C. Venter et al., Science 280, 1540 (1998). 15. M. D. Adams, J. J. Sekelsky, Nat. Rev. Genet. 3, 189 (2002). 16. U. S. Eggert et al., PLoS Biol. 2, e379 (2004). 17. R. Dasgupta, N. Perrimon, Oncogene 23, 8359 (2004). 18. M. Boutros et al., Science 303, 832 (2004). 19. A. A. Kiger et al., J. Biol. 2, 27 (2003). 20. V. Korinek et al., Nat. Genet. 19, 379 (1998). 21. V. Korinek et al., Mol....
متن کاملImportance of microRNAs in skin morphogenesis and diseases.
MicroRNAs (miRNAs) are small (20-22 nt), non-coding RNAs involved in post-transcriptional gene silencing. Their binding to the 3' UTR of target mRNAs influences the translation or stability of the transcripts. miRNAs have been shown to regulate several developmental and physiological processes, including stem cell differentiation and the immune response. Recent findings report their involvement...
متن کاملCadherins in brain morphogenesis and wiring.
Cadherins are Ca(2+)-dependent cell-cell adhesion molecules that play critical roles in animal morphogenesis. Various cadherin-related molecules have also been identified, which show diverse functions, not only for the regulation of cell adhesion but also for that of cell proliferation and planar cell polarity. During the past decade, understanding of the roles of these molecules in the nervous...
متن کاملFine-tuning the brain: MicroRNAs.
The brain is of bewildering complexity and numerous genes and signaling molecules have been described that affect the architecture and functioning of specific neuronal circuits. Recent evidence from genome analysis revealed the existence of a large group of novel RNA molecules with unexpected properties. One such group is called microRNAs, which are small 21-23 nucleotides RNA molecules that ar...
متن کاملRole of hlx1 in zebrafish brain morphogenesis.
hlx1 is a related homeobox gene expressed in a dynamic spatiotemporal expression pattern during development of the zebrafish brain. The homologues of hlx1, mouse dbx1 and Xenopus Xdbx, are known to play a role in the specification of neurons in the spinal cord. However, the role of these molecules in the brain is less well known. We have used two different approaches to elucidate a putative fun...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2005
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn1718